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Genomic Alterations and Tumor Mutation Burden in Merkel Cell Carcinoma

IMPORTANCE: Merkel cell carcinoma (MCC) is a rare and highly aggressive cutaneous neuroendocrine carcinoma with increasing incidence. Cytotoxic chemotherapy and checkpoint inhibitors provide treatment options in the metastatic setting; however, there are no approved or standard of care targeted ther...

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Detalles Bibliográficos
Autores principales: Brazel, Danielle, Kumar, Priyanka, Doan, Hung, Pan, Tianyu, Shen, Weining, Gao, Ling, Moyers, Justin T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856969/
https://www.ncbi.nlm.nih.gov/pubmed/36602798
http://dx.doi.org/10.1001/jamanetworkopen.2022.49674