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Disruption of CCL2 in Mesenchymal Stem Cells as an Anti-Tumor Approach against Prostate Cancer

SIMPLE SUMMARY: Cancer cells and mesenchymal stem cells (MSCs) secrete C-C motif chemokine ligand 2 (CCL2), a small protein that attracts tumor-associated macrophages (TAMs), which promotes malignant progression, such as drug resistance and metastasis. In addition, MSCs can also be recruited by CCL2...

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Detalles Bibliográficos
Autores principales: Bui, Quoc Thang, Lee, Kuan-Der, Fan, Yu-Ching, Lewis, Branwen S., Deng, Lih-Wen, Tsai, Yuan-Chin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9857005/
https://www.ncbi.nlm.nih.gov/pubmed/36672395
http://dx.doi.org/10.3390/cancers15020441