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Current Understanding of DDX41 Mutations in Myeloid Neoplasms

SIMPLE SUMMARY: The DEAD-box RNA helicase 41, DDX41, is one of the most frequently identified mutations in myeloid neoplasms with germline predispositions, which represents 2% of the entire MDS/AML population. DDX41 is located at 5q35.3, and its mutation has unique features of male predominance and...

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Detalles Bibliográficos
Autores principales: Kim, Kunhwa, Ong, Faustine, Sasaki, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9857085/
https://www.ncbi.nlm.nih.gov/pubmed/36672294
http://dx.doi.org/10.3390/cancers15020344