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Reduced Cell–ECM Interactions in the EpiSC Colony Center Cause Heterogeneous Differentiation

Mechanoregulation of cell–extracellular matrix (ECM) interactions are crucial for dictating pluripotent stem cell differentiation. However, not all pluripotent cells respond homogeneously which results in heterogeneous cell populations. When cells, such as mouse epiblast stem cells (EpiSCs), are cul...

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Detalles Bibliográficos
Autores principales: Amar, Kshitij, Saha, Sanjoy, Debnath, Avishek, Weng, Chun Hung, Roy, Arpan, Han, Kyu Young, Chowdhury, Farhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9857087/
https://www.ncbi.nlm.nih.gov/pubmed/36672261
http://dx.doi.org/10.3390/cells12020326