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Evaluation of zoledronate for the treatment of canine stage III osteosarcoma: A phase II study

BACKGROUND: Greater than 90% of dogs with appendicular osteosarcoma will develop pulmonary metastasis despite the standard of care. Available treatments have limited efficacy for stage III disease. Zoledronate, a bisphosphonate, induces apoptosis of canine osteosarcoma cells and appears to modulate...

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Detalles Bibliográficos
Autores principales: Smith, Ashley A., Lindley, Stephanie E.S., Almond, Greg T., Bergman, Noelle S., Matz, Brad M., Smith, Annette N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9857128/
https://www.ncbi.nlm.nih.gov/pubmed/36398717
http://dx.doi.org/10.1002/vms3.1000