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E3 Ubiquitin Ligase NEDD4 Affects Estrogen Receptor α Expression and the Prognosis of Patients with Hormone Receptor-Positive Breast Cancer

SIMPLE SUMMARY: Hormone therapy for breast cancer targets estrogen receptors to inhibit the growth of cancer cells. We previously reported that neural precursor cell-expressed developmentally downregulated 4–1 (NEDD4) promotes the degradation of the estrogen receptor α. Therefore, NEDD4 may affect t...

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Detalles Bibliográficos
Autores principales: Natori, Yutaka, Suga, Junko, Tokuda, Emi, Tachibana, Kazunoshin, Imai, Jun-ichi, Honma, Reiko, Azami, Yusuke, Noda, Masaru, Sasaki, Eisaku, Watanabe, Shinya, Ohtake, Tohru, Saji, Shigehira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9857178/
https://www.ncbi.nlm.nih.gov/pubmed/36672488
http://dx.doi.org/10.3390/cancers15020539