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Shallow Whole-Genome Sequencing of Cell-Free DNA (cfDNA) Detects Epithelial Ovarian Cancer and Predicts Patient Prognosis

SIMPLE SUMMARY: Despite the progress in diagnostics and therapeutics, epithelial ovarian cancer (EOC) remains a fatal disease. Using shallow whole-genome sequencing (WGS), we identified copy number variations (CNVs). In addition, we quantified chromosomal instability using genome-wide instability an...

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Detalles Bibliográficos
Autores principales: Bak, Seong Eun, Kim, Hanwool, Ho, Jung Yoon, Cho, Eun-Hae, Lee, Junnam, Youn, Sung Min, Park, Seong-Woo, Han, Mi-Ryung, Hur, Soo Young, Lee, Sung Jong, Choi, Youn Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9857189/
https://www.ncbi.nlm.nih.gov/pubmed/36672479
http://dx.doi.org/10.3390/cancers15020530