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Genome-Wide Methylation Changes Associated with Replicative Senescence and Differentiation in Endothelial and Bone Marrow Mesenchymal Stromal Cells

Bone marrow mesenchymal stromal cells (BMSCs) are multipotent cells able to self-renew and differentiate, depending on the microenvironment, into adipocytes and osteoblasts. These cells have a limited number of replications and enter replicative senescence during in vitro expansion. The role of DNA...

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Detalles Bibliográficos
Autores principales: Giuliani, Angelica, Bacalini, Maria Giulia, Ramini, Deborah, Mensà, Emanuela, Giordani, Chiara, Xumerle, Luciano, Garagnani, Paolo, Olivieri, Fabiola, Procopio, Antonio Domenico, Rippo, Maria Rita, Sabbatinelli, Jacopo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9857206/
https://www.ncbi.nlm.nih.gov/pubmed/36672222
http://dx.doi.org/10.3390/cells12020285