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Regulation of EWSR1-FLI1 Function by Post-Transcriptional and Post-Translational Modifications

SIMPLE SUMMARY: Ewing sarcoma is a malignant pediatric bone cancer currently lacking targeted therapy. In the US there are ~200 patients diagnosed each year and relapse is associated with resistance to the standard-of-care chemotherapy. Thus, it remains an urgent unmet medical need to develop effect...

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Detalles Bibliográficos
Autores principales: Yu, Le, Davis, Ian J., Liu, Pengda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9857208/
https://www.ncbi.nlm.nih.gov/pubmed/36672331
http://dx.doi.org/10.3390/cancers15020382