Libertellenone T, a Novel Compound Isolated from Endolichenic Fungus, Induces G2/M Phase Arrest, Apoptosis, and Autophagy by Activating the ROS/JNK Pathway in Colorectal Cancer Cells

SIMPLE SUMMARY: Libertellenone T (B) is a natural product derived from the secondary metabolites of the endolichenic fungus, Pseudoplectania sp. In this study, we investigated the underlying molecular mechanisms that induce the apoptotic cell death of the colorectal cancer cell line, Caco2, in respo...

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Detalles Bibliográficos
Autores principales: Gamage, Chathurika D. B., Kim, Jeong-Hyeon, Yang, Yi, Taş, İsa, Park, So-Yeon, Zhou, Rui, Pulat, Sultan, Varlı, Mücahit, Hur, Jae-Seoun, Nam, Sang-Jip, Kim, Hangun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9857212/
https://www.ncbi.nlm.nih.gov/pubmed/36672439
http://dx.doi.org/10.3390/cancers15020489

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9857212/
https://www.ncbi.nlm.nih.gov/pubmed/36672439
http://dx.doi.org/10.3390/cancers15020489

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