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Notch Signaling Suppresses Melanoma Tumor Development in BRAF/Pten Mice

SIMPLE SUMMARY: It is now well recognized that alterations in both oncogenic and tumor suppressor genes are required for cutaneous melanoma tumorigenesis. Although Notch signaling has been implicated in many aspects of melanoma biology, the exact role Notch genes play in melanomagenesis is not compl...

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Detalles Bibliográficos
Autores principales: Mikheil, Dareen, Prabhakar, Kirthana, Ng, Tun Lee, Teertam, Sireesh, Longley, B. Jack, Newton, Michael A., Setaluri, Vijayasaradhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9857214/
https://www.ncbi.nlm.nih.gov/pubmed/36672468
http://dx.doi.org/10.3390/cancers15020519