Autophagy Activation Associates with Suppression of Prion Protein and Improved Mitochondrial Status in Glioblastoma Cells

Cells from glioblastoma multiforme (GBM) feature up-regulation of the mechanistic Target of Rapamycin (mTOR), which brings deleterious effects on malignancy and disease course. At the cellular level, up-regulation of mTOR affects a number of downstream pathways and suppresses autophagy, which is rel...

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Detalles Bibliográficos
Autores principales: Lenzi, Paola, Busceti, Carla L., Lazzeri, Gloria, Ferese, Rosangela, Biagioni, Francesca, Salvetti, Alessandra, Pompili, Elena, De Franchis, Valerio, Puglisi-Allegra, Stefano, Frati, Alessandro, Ferrucci, Michela, Fornai, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9857229/
https://www.ncbi.nlm.nih.gov/pubmed/36672156
http://dx.doi.org/10.3390/cells12020221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9857229/
https://www.ncbi.nlm.nih.gov/pubmed/36672156
http://dx.doi.org/10.3390/cells12020221

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