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NFκB-Mediated Expression of Phosphoinositide 3-Kinase δ Is Critical for Mesenchymal Transition in Retinal Pigment Epithelial Cells

Epithelial mesenchymal transition (EMT) plays a vital role in a variety of human diseases including proliferative vitreoretinopathy (PVR), in which retinal pigment epithelial (RPE) cells play a key part. Transcriptomic analysis showed that the phosphoinositide 3-kinase (PI3K)/Akt signaling pathway w...

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Detalles Bibliográficos
Autores principales: Han, Haote, Yang, Yanhui, Han, Zhuo, Wang, Luping, Dong, Lijun, Qi, Hui, Liu, Bing, Tian, Jingkui, Vanhaesebroeck, Bart, Kazlauskas, Andrius, Zhang, Guoming, Zhang, Shaochong, Lei, Hetian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9857235/
https://www.ncbi.nlm.nih.gov/pubmed/36672142
http://dx.doi.org/10.3390/cells12020207