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Early Subcellular Hepatocellular Alterations in Mice Post Hydrodynamic Transfection: An Explorative Study

SIMPLE SUMMARY: Our electron microscopic (EM) findings indicate that hydrodynamic based plasmid transfer to the hepatocytes possibly occurs via active or passive endocytosis with the plasmid entrapment in membrane bound multiple vesicle and vacuoles. Our ultramorphological study on the vacuole conta...

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Detalles Bibliográficos
Autores principales: Yasser, Mohd, Ribback, Silvia, Evert, Katja, Utpatel, Kirsten, Annweiler, Katharina, Evert, Matthias, Dombrowski, Frank, Calvisi, Diego F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9857294/
https://www.ncbi.nlm.nih.gov/pubmed/36672277
http://dx.doi.org/10.3390/cancers15020328