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Role of Moonlighting Proteins in Disease: Analyzing the Contribution of Canonical and Moonlighting Functions in Disease Progression

The term moonlighting proteins refers to those proteins that present alternative functions performed by a single polypeptide chain acquired throughout evolution (called canonical and moonlighting, respectively). Over 78% of moonlighting proteins are involved in human diseases, 48% are targeted by cu...

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Detalles Bibliográficos
Autores principales: Huerta, Mario, Franco-Serrano, Luis, Amela, Isaac, Perez-Pons, Josep Antoni, Piñol, Jaume, Mozo-Villarías, Angel, Querol, Enrique, Cedano, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9857295/
https://www.ncbi.nlm.nih.gov/pubmed/36672169
http://dx.doi.org/10.3390/cells12020235