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Cord Blood Plasma and Placental Mesenchymal Stem Cells-Derived Exosomes Increase Ex Vivo Expansion of Human Cord Blood Hematopoietic Stem Cells While Maintaining Their Stemness

Background: Mesenchymal stem cells (MSCs) have been used for ex vivo expansion of umbilical cord blood (UCB) hematopoietic stem cells (HSCs) to maintain their primitive characters and long-term reconstitution abilities during transplantation. Therapeutic effects of MSCs mainly rely on paracrine mech...

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Detalles Bibliográficos
Autores principales: Teleb, Rasha S., Abdul-Hafez, Amal, Othman, Amira, Ahmed, Ahmed El-Abd, Elsaid, Abdelrahman A., Arif, Hattan, Zarea, Ahmed A., Abdulmageed, Mohammed, Mohamed, Hend, Ibrahim, Sherif Abdelfattah, Thiruvenkataramani, Ranga P., Mohamed, Tarek, Kanada, Masamitsu, Madhukar, Burra V., Arellano, Myrna Gonzalez, Sayed, Mohammed M., Qubaisy, Heba M., Omar, Said A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9857343/
https://www.ncbi.nlm.nih.gov/pubmed/36672185
http://dx.doi.org/10.3390/cells12020250