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Association of Inherited Genetic Factors With Drug-Induced Hepatic Damage Among Children With Acute Lymphoblastic Leukemia

IMPORTANCE: Acute lymphoblastic leukemia (ALL) is the most common childhood cancer. Hepatotoxic effects, including hyperbilirubinemia and elevated alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels, are common during all phases of therapy and are linked to several chemotherap...

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Detalles Bibliográficos
Autores principales: Yang, Wenjian, Karol, Seth E., Hoshitsuki, Keito, Lee, Shawn, Larsen, Eric C., Winick, Naomi, Carroll, William L., Loh, Mignon L., Raetz, Elizabeth A., Hunger, Stephen P., Winter, Stuart S., Dunsmore, Kimberly P., Devidas, Meenakshi, Relling, Mary V., Yang, Jun J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9857512/
https://www.ncbi.nlm.nih.gov/pubmed/36580335
http://dx.doi.org/10.1001/jamanetworkopen.2022.48803