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Immune Checkpoint Glycoproteins Have Polymorphism: Are Monoclonal Antibodies Too Specific?

Since the 2018 Nobel prize in medicine was granted to the discovery of immune escape by cancer cells, billions of dollars have been spent on a new form of cancer immunotherapy called immune checkpoint inhibition (ICI). In this treatment modality, monoclonal antibodies (mAbs) are used to block cell-s...

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Detalles Bibliográficos
Autores principales: Jalalizadeh, Mehrsa, Yadollahvandmiandoab, Reza, Reis, Leonardo Oliveira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9857673/
https://www.ncbi.nlm.nih.gov/pubmed/36661747
http://dx.doi.org/10.3390/curroncol30010098