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A multi-view latent variable model reveals cellular heterogeneity in complex tissues for paired multimodal single-cell data

MOTIVATION: Single-cell multimodal assays allow us to simultaneously measure two different molecular features of the same cell, enabling new insights into cellular heterogeneity, cell development and diseases. However, most existing methods suffer from inaccurate dimensionality reduction for the joi...

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Detalles Bibliográficos
Autores principales: Wang, Yuwei, Lian, Bin, Zhang, Haohui, Zhong, Yuanke, He, Jie, Wu, Fashuai, Reinert, Knut, Shang, Xuequn, Yang, Hui, Hu, Jialu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9857983/
https://www.ncbi.nlm.nih.gov/pubmed/36622018
http://dx.doi.org/10.1093/bioinformatics/btad005