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LKB1 Loss Assessed by Immunohistochemistry as a Prognostic Marker to First-Line Therapy in Advanced Non-Small-Cell Lung Cancer

(1) Background: Liver kinase B1 (LKB1) is a tumor suppressor gene involved in cell growth and metabolism. However, its alterations are not routinely assessed for guiding therapy in clinical practice. We assessed LKB1 expression by immunohistochemistry as a potential biomarker. (2) Methods: This bice...

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Detalles Bibliográficos
Autores principales: Avilés-Salas, Alejandro, Díaz-García, Diego A., Lara-Mejía, Luis, Cardona, Andrés F., Orozco-Morales, Mario, Catalán, Rodrigo, Hernández-Pedro, Norma Y., Rios-Garcia, Eduardo, Ramos-Ramírez, Maritza, Arrieta, Oscar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9857995/
https://www.ncbi.nlm.nih.gov/pubmed/36661676
http://dx.doi.org/10.3390/curroncol30010027