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Deciphering the Mechanism of Wogonin, a Natural Flavonoid, on the Proliferation of Pulmonary Arterial Smooth Muscle Cells by Integrating Network Pharmacology and In Vitro Validation

Wogonin is one of the main active components of Scutellaria baicalensis, which has anti-inflammatory, anti-angiogenesis, and anti-fibrosis effects. Nevertheless, the effect of wogonin on pulmonary hypertension (PH) still lacks systematic research. This study aims to elucidate the potential mechanism...

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Detalles Bibliográficos
Autores principales: Cui, Lidan, Zeng, Zuomei, Wang, Xinyue, Yuan, Tianyi, Wang, Can, Liu, Dianlong, Guo, Jian, Chen, Yucai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9858126/
https://www.ncbi.nlm.nih.gov/pubmed/36661523
http://dx.doi.org/10.3390/cimb45010037