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Solid Organ Transplantation Is Associated with an Increased Rate of Mismatch Repair Deficiency and PIK3CA Mutations in Colorectal Cancer

Solid organ transplants are associated with a modestly increased risk of colorectal cancers (CRC). However, the molecular profile of these cancers has not been described. We hypothesized that transplant-related immunosuppression may promote development of more immunogenic tumors as suggested by a hi...

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Detalles Bibliográficos
Autores principales: Christenson, Eric S., Lee, Valerie, Wang, Hao, Yarchoan, Mark, De Jesus-Acosta, Ana, Azad, Nilo, Gurakar, Ahmet, Lin, Ming-Tseh, Le, Dung T., Brennan, Daniel C., Jaffee, Elizabeth M., Bever, Katherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9858144/
https://www.ncbi.nlm.nih.gov/pubmed/36661655
http://dx.doi.org/10.3390/curroncol30010006