Increased mTOR Signaling and Impaired Autophagic Flux Are Hallmarks of SARS-CoV-2 Infection

The COVID-19 (Coronavirus Disease 2019), caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), severely affects mainly individuals with pre-existing comorbidities. Here our aim was to correlate the mTOR (mammalian/mechanistic Target of Rapamycin) and autophagy pathways with the...

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Detalles Bibliográficos
Autores principales: Zambalde, Érika Pereira, Dias, Thomaz Luscher, Maktura, Grazielle Celeste, Amorim, Mariene R., Brenha, Bianca, Santos, Luana Nunes, Buscaratti, Lucas, Elston, João Gabriel de Angeli, Mancini, Mariana Camargo Silva, Pavan, Isadora Carolina Betim, Toledo-Teixeira, Daniel A., Bispo-dos-Santos, Karina, Parise, Pierina L., Morelli, Ana Paula, da Silva, Luiz Guilherme Salvino, de Castro, Ícaro Maia Santos, Saccon, Tatiana D., Mori, Marcelo A., Granja, Fabiana, Nakaya, Helder I., Proenca-Modena, Jose Luiz, Marques-Souza, Henrique, Simabuco, Fernando Moreira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9858158/
https://www.ncbi.nlm.nih.gov/pubmed/36661509
http://dx.doi.org/10.3390/cimb45010023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9858158/
https://www.ncbi.nlm.nih.gov/pubmed/36661509
http://dx.doi.org/10.3390/cimb45010023

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