Combining nano-differential scanning fluorimetry and microscale thermophoresis to investigate VDAC1 interaction with small molecules

The mitochondrial voltage-dependent anion channel 1 (VDAC1) plays a central role in metabolism and apoptosis, which makes it a promising therapeutic target. Nevertheless, molecular mechanisms governing VDAC1 functioning remain unclear. Small-molecule ligands specifically interacting with the channel...

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Detalles Bibliográficos
Autores principales: Gorny, Hubert, Mularoni, Angélique, Delcros, Jean-Guy, Freton, Céline, Preto, Jordane, Krimm, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9858421/
https://www.ncbi.nlm.nih.gov/pubmed/36650907
http://dx.doi.org/10.1080/14756366.2022.2121821

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9858421/
https://www.ncbi.nlm.nih.gov/pubmed/36650907
http://dx.doi.org/10.1080/14756366.2022.2121821

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