Cargando…

Combining nano-differential scanning fluorimetry and microscale thermophoresis to investigate VDAC1 interaction with small molecules

The mitochondrial voltage-dependent anion channel 1 (VDAC1) plays a central role in metabolism and apoptosis, which makes it a promising therapeutic target. Nevertheless, molecular mechanisms governing VDAC1 functioning remain unclear. Small-molecule ligands specifically interacting with the channel...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gorny, Hubert, Mularoni, Angélique, Delcros, Jean-Guy, Freton, Céline, Preto, Jordane, Krimm, Isabelle
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2023
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9858421/ https://www.ncbi.nlm.nih.gov/pubmed/36650907 http://dx.doi.org/10.1080/14756366.2022.2121821

Ejemplares similares

A Deep Dive into VDAC1 Conformational Diversity Using All-Atom Simulations Provides New Insights into the Structural Origin of the Closed States
por: Preto, Jordane, et al.
Publicado: (2022)

Absolute Quantification of Noncoding RNA by Microscale Thermophoresis
por: Jacob, Dominik, et al.
Publicado: (2019)

The intrinsically disordered N-terminus of the voltage-dependent anion channel
por: Preto, Jordane, et al.
Publicado: (2021)

Reproducibility and accuracy of microscale thermophoresis in the NanoTemper Monolith: a multi laboratory benchmark study
por: López-Méndez, Blanca, et al.
Publicado: (2021)

Kinetic Microscale Thermophoresis for Simultaneous Measurement of Binding Affinity and Kinetics
por: Stein, Julian A. C., et al.
Publicado: (2021)

Applications of the Microscale Thermophoresis Binding Assay in COVID-19 Research
por: Nydegger, Damian T., et al.
Publicado: (2023)

Correction to: Reproducibility and accuracy of microscale thermophoresis in the NanoTemper Monolith: a multi laboratory benchmark study
por: López-Méndez, Blanca, et al.
Publicado: (2021)

An Automated Microscale Thermophoresis Screening Approach for Fragment-Based Lead Discovery
por: Linke, Pawel, et al.
Publicado: (2015)

Quantitative analysis of protease recognition by inhibitors in plasma using microscale thermophoresis
por: Dau, T., et al.
Publicado: (2016)

Microscale Thermophoresis as a Screening Tool to Predict Melanin Binding of Drugs
por: Hellinen, Laura, et al.
Publicado: (2020)

Nano Differential Scanning Fluorimetry as a Rapid Stability Assessment Tool in the Nanoformulation of Proteins
por: Lisina, Sofia, et al.
Publicado: (2023)

Label-Free Microscale Thermophoresis Discriminates Sites and Affinity of Protein–Ligand Binding**
por: Seidel, Susanne A I, et al.
Publicado: (2012)

PD-1/PD-L1 binding studies using microscale thermophoresis
por: Magnez, Romain, et al.
Publicado: (2017)

Characterization of human aquaporin protein-protein interactions using microscale thermophoresis (MST)
por: Al-Jubair, Tamim, et al.
Publicado: (2022)

Microscale Thermophoresis and Molecular Modelling to Explore the Chelating Drug Transportation in the Milk to Infant
por: Asmari, Mufarreh, et al.
Publicado: (2022)

Microscale Thermophoresis as a Tool to Study Protein Interactions and Their Implication in Human Diseases
por: Magnez, Romain, et al.
Publicado: (2022)

Non-covalent dyes in microscale thermophoresis for studying RNA ligand interactions and modifications
por: Kallert, Elisabeth, et al.
Publicado: (2023)

MUC4-ErbB2 Oncogenic Complex: Binding studies using Microscale Thermophoresis
por: Liberelle, Maxime, et al.
Publicado: (2019)

Microscale thermophoresis as a powerful tool for screening glycosyltransferases involved in cell wall biosynthesis
por: Shao, Wanchen, et al.
Publicado: (2020)

Novel Method for Quantifying AhR-Ligand Binding Affinities Using Microscale Thermophoresis
por: Stinn, Anne, et al.
Publicado: (2021)

Microscale Thermophoresis Reveals Oxidized Glutathione as High-Affinity Ligand of Mal d 1
por: Chebib, Soraya, et al.
Publicado: (2021)

The Acid-Base/Deprotonation Equilibrium Can Be Studied with a MicroScale Thermophoresis (MST)
por: Nowak, Paweł Mateusz, et al.
Publicado: (2022)

Solution composition dependent Soret coefficient using commercial MicroScale Thermophoresis instrument
por: Pulyala, Praneetha, et al.
Publicado: (2023)

Surface plasmon resonance and microscale thermophoresis approaches for determining the affinity of perforin for calcium ions
por: Naneh, Omar, et al.
Publicado: (2023)

Protocol for performing and optimizing differential scanning fluorimetry experiments
por: Wu, Taiasean, et al.
Publicado: (2023)

Nano Differential Scanning Fluorimetry-Based Thermal Stability Screening and Optimal Buffer Selection for Immunoglobulin G
por: Kim, Soo Hyun, et al.
Publicado: (2021)

Label-free measurement of antimicrobial peptide interactions with lipid vesicles and nanodiscs using microscale thermophoresis
por: Rainsford, Philip, et al.
Publicado: (2023)

Publisher Correction: MUC4-ErbB2 Oncogenic Complex: Binding studies using Microscale Thermophoresis
por: Liberelle, Maxime, et al.
Publicado: (2020)

Determination of Protein-ligand Interactions Using Differential Scanning Fluorimetry
por: Vivoli, Mirella, et al.
Publicado: (2014)

Bayesian Analysis of MicroScale Thermophoresis Data to Quantify Affinity of Protein:Protein Interactions with Human Survivin
por: Garcia-Bonete, Maria-Jose, et al.
Publicado: (2017)

Studying Interactions between 2’-O-Me-Modified Inhibitors and MicroRNAs Utilizing Microscale Thermophoresis
por: Herkt, Markus, et al.
Publicado: (2019)

Translesion DNA Synthesis Across Lesions Induced by Oxidative Products of Pyrimidines: An Insight into the Mechanism by Microscale Thermophoresis
por: Hrabina, Ondrej, et al.
Publicado: (2019)

Theory and applications of differential scanning fluorimetry in early-stage drug discovery
por: Gao, Kai, et al.
Publicado: (2020)

Conformationally responsive dyes enable protein-adaptive differential scanning fluorimetry
por: Wu, Taiasean, et al.
Publicado: (2023)

Using Microscale Thermophoresis to Characterize Hits from High-Throughput Screening: A European Lead Factory Perspective
por: Rainard, Julie M., et al.
Publicado: (2018)

Differential Scanning Fluorimetry provides high throughput data on silk protein transitions.
por: Vollrath, Fritz, et al.
Publicado: (2014)

Application of temperature-responsive HIS-tag fluorophores to differential scanning fluorimetry screening of small molecule libraries
por: Ronzetti, Michael H., et al.
Publicado: (2022)

Near-native, site-specific and purification-free protein labeling for quantitative protein interaction analysis by MicroScale Thermophoresis
por: Bartoschik, Tanja, et al.
Publicado: (2018)

Separation of Nano- and Microparticle Flows Using Thermophoresis in Branched Microfluidic Channels
por: Tsuji, Tetsuro, et al.
Publicado: (2019)

Low cost, microcontroller based heating device for multi-wavelength differential scanning fluorimetry
por: Hoeser, Jo, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_pfakspefp4nkklllvl0ne3ehe4