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Cathelicidin LL-37 promotes EMT, migration and metastasis of hepatocellular carcinoma cells in vitro and mouse model

The effect of cathelicidin hCAP18/LL-37 in hepatocellular carcinoma (HCC) metastasis remains unclear. Here, we confirmed that LL-37 expression enhanced endothelial-mesenchymal transition (EMT), migration and invasion in HCC cells. And the HER2/EGFR-MAPK/ERK signal participated in the process above....

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Detalles Bibliográficos
Autores principales: Zhang, Huidan, Yuan, Xueli, Yang, Yaxin, Wanyan, Yangke, Tao, Liping, Chen, Yuqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9858423/
https://www.ncbi.nlm.nih.gov/pubmed/36656313
http://dx.doi.org/10.1080/19336918.2023.2168231