Cargando…

Cathelicidin LL-37 promotes EMT, migration and metastasis of hepatocellular carcinoma cells in vitro and mouse model

The effect of cathelicidin hCAP18/LL-37 in hepatocellular carcinoma (HCC) metastasis remains unclear. Here, we confirmed that LL-37 expression enhanced endothelial-mesenchymal transition (EMT), migration and invasion in HCC cells. And the HER2/EGFR-MAPK/ERK signal participated in the process above....

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Huidan, Yuan, Xueli, Yang, Yaxin, Wanyan, Yangke, Tao, Liping, Chen, Yuqing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9858423/ https://www.ncbi.nlm.nih.gov/pubmed/36656313 http://dx.doi.org/10.1080/19336918.2023.2168231

Ejemplares similares

Cathelicidin hCAP18/LL-37 promotes cell proliferation and suppresses antitumor activity of 1,25(OH)(2)D(3) in hepatocellular carcinoma
por: Zhang, Huidan, et al.
Publicado: (2022)

The Role of Cathelicidin LL-37 in Cancer Development
por: Piktel, Ewelina, et al.
Publicado: (2015)

Efficacy of Cathelicidin LL-37 in an MRSA Wound Infection Mouse Model
por: Simonetti, Oriana, et al.
Publicado: (2021)

Cathelicidin LL-37 in Health and Diseases of the Oral Cavity
por: Tokajuk, Joanna, et al.
Publicado: (2022)

Cathelicidin LL37 Promotes Osteogenic Differentiation in vitro and Bone Regeneration in vivo
por: Li, Lunhao, et al.
Publicado: (2021)

Pulmonary defense and the human cathelicidin hCAP-18/LL-37
por: Fahy, R. J., et al.
Publicado: (2005)

Cathelicidin LL-37: An Antimicrobial Peptide with a Role in Inflammatory Skin Disease
por: Reinholz, Markus, et al.
Publicado: (2012)

Transformation of Human Cathelicidin LL-37 into Selective, Stable, and Potent Antimicrobial Compounds
por: Wang, Guangshun, et al.
Publicado: (2014)

Upregulation of human β-defensin-3 and cathelicidin LL-37 in Kaposi’s sarcoma
por: Fathy, Hanan, et al.
Publicado: (2012)

The Human Cathelicidin Antimicrobial Peptide LL-37 and Mimics are Potential Anticancer Drugs
por: Kuroda, Kengo, et al.
Publicado: (2015)

Human cathelicidin LL-37 enhance the antibiofilm effect of EGCG on Streptococcus mutans
por: Guo, Yi-jie, et al.
Publicado: (2016)

The impact of cathelicidin, the human antimicrobial peptide LL-37 in urinary tract infections
por: Babikir, Ibrahim H., et al.
Publicado: (2018)

Significance and Diagnostic Role of Antimicrobial Cathelicidins (LL-37) Peptides in Oral Health
por: Khurshid, Zohaib, et al.
Publicado: (2017)

The Human Cathelicidin LL-37 Has Antiviral Activity against Respiratory Syncytial Virus
por: Currie, Silke M., et al.
Publicado: (2013)

Serum concentrations of antimicrobial peptide cathelicidin LL-37 in patients with bacterial lung infections
por: Majewski, Karol, et al.
Publicado: (2018)

Expression and function of cathelicidin hCAP18/LL-37 in chronic lymphocytic leukemia
por: Podaza, Enrique, et al.
Publicado: (2020)

Cathelicidin LL-37: A new important molecule in the pathophysiology of systemic lupus erythematosus
por: Moreno-Angarita, Alejandro, et al.
Publicado: (2019)

Secondary necrosis of apoptotic neutrophils induced by the human cathelicidin LL-37 is not proinflammatory to phagocytosing macrophages
por: Li, Hsin-Ni, et al.
Publicado: (2009)

The influence of cathelicidin LL37 in human anti-neutrophils cytoplasmic antibody (ANCA)-associated vasculitis
por: Zhang, Ying, et al.
Publicado: (2013)

The Human Cathelicidin Antimicrobial Peptide LL-37 as a Potential Treatment for Polymicrobial Infected Wounds
por: Duplantier, Allen J., et al.
Publicado: (2013)

Heparan Sulfate Proteoglycan–Involving Immunomodulation by Cathelicidin Antimicrobial Peptides LL-37 and PR-39
por: Kaneider, Nicole C., et al.
Publicado: (2007)

Cathelicidin LL-37 restoring glucocorticoid function in smoking and lipopolysaccharide-induced airway inflammation in rats
por: Weng, Jian-Zhen, et al.
Publicado: (2019)

Cathelicidins PMAP-36, LL-37 and CATH-2 are similar peptides with different modes of action
por: Scheenstra, Maaike R., et al.
Publicado: (2019)

Retraction Note: Human cathelicidin LL-37 enhance the antibiofilm effect of EGCG on Streptococcus mutans
por: Guo, Yi-jie, et al.
Publicado: (2017)

Formulation and candidacidal activity of magnetic nanoparticles coated with cathelicidin LL-37 and ceragenin CSA-13
por: Niemirowicz, Katarzyna, et al.
Publicado: (2017)

Therapeutic Potential of Cathelicidin Peptide LL-37, an Antimicrobial Agent, in a Murine Sepsis Model
por: Nagaoka, Isao, et al.
Publicado: (2020)

Citrullination Alters the Antiviral and Immunomodulatory Activities of the Human Cathelicidin LL-37 During Rhinovirus Infection
por: Casanova, Víctor, et al.
Publicado: (2020)

Sequence determinants in the cathelicidin LL-37 that promote inflammation via presentation of RNA to scavenger receptors
por: Kulkarni, Nikhil N., et al.
Publicado: (2021)

Design, synthesis, and characterization of non-hemolytic antimicrobial peptides related to human cathelicidin LL-37
por: Krishnamoorthy, Rajavenkatesh, et al.
Publicado: (2023)

Epithelial-Immune Cell Crosstalk Determines the Activation of Immune Cells In Vitro by the Human Cathelicidin LL-37 at Low Physiological Concentrations
por: Bogdanov, Ivan V., et al.
Publicado: (2023)

Cathelicidin antimicrobial peptide LL-37 in psoriasis enables keratinocyte reactivity against TLR9 ligands
por: Morizane, Shin, et al.
Publicado: (2011)

Antiviral Activity and Increased Host Defense against Influenza Infection Elicited by the Human Cathelicidin LL-37
por: Barlow, Peter G., et al.
Publicado: (2011)

Antimicrobial Cathelicidin Peptide LL-37 Inhibits the LPS/ATP-Induced Pyroptosis of Macrophages by Dual Mechanism
por: Hu, Zhongshuang, et al.
Publicado: (2014)

Magnetic nanoparticles enhance the anticancer activity of cathelicidin LL-37 peptide against colon cancer cells
por: Niemirowicz, Katarzyna, et al.
Publicado: (2015)

Antiviral Activity of the Human Cathelicidin, LL-37, and Derived Peptides on Seasonal and Pandemic Influenza A Viruses
por: Tripathi, Shweta, et al.
Publicado: (2015)

Human cathelicidin, LL-37, inhibits respiratory syncytial virus infection in polarized airway epithelial cells
por: Harcourt, Jennifer L., et al.
Publicado: (2016)

Cathelicidin LL-37 Affects Surface and Intracellular Toll-Like Receptor Expression in Tissue Mast Cells
por: Agier, Justyna, et al.
Publicado: (2018)

Anaerobic bacteria growth in the presence of cathelicidin LL-37 and selected ceragenins delivered as magnetic nanoparticles cargo
por: Durnaś, Bonita, et al.
Publicado: (2017)

Candidacidal Activity of Selected Ceragenins and Human Cathelicidin LL-37 in Experimental Settings Mimicking Infection Sites
por: Durnaś, Bonita, et al.
Publicado: (2016)

The structure of the antimicrobial human cathelicidin LL-37 shows oligomerization and channel formation in the presence of membrane mimics
por: Sancho-Vaello, Enea, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_gcue51g8ic3rqqb0rq5m3ug26i