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Qiangjing tablets ameliorate asthenozoospermia via mitochondrial ubiquitination and mitophagy mediated by LKB1/AMPK/ULK1 signaling

CONTEXT: Therapeutic effects of Qiangjing tablets (QJT) on sperm vitality and asthenozoospermia (AZS) have been confirmed. However, the mechanism of action remains unclear. OBJECTIVE: This study investigates the effects of QJT on AZS and the underlying mechanism of action. MATERIALS AND METHODS: Six...

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Detalles Bibliográficos
Autores principales: Li, Guangsen, Xu, Yuanjie, Li, Yingxi, Chang, Degui, Zhang, Peihai, Ma, Ziyang, Chen, Di’ang, You, Yaodong, Huang, Xiaopeng, Cai, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9858429/
https://www.ncbi.nlm.nih.gov/pubmed/36655371
http://dx.doi.org/10.1080/13880209.2023.2168021