Identification of new benzimidazole-triazole hybrids as anticancer agents: multi-target recognition, in vitro and in silico studies

Multi-target inhibitors represent useful anticancer agents with superior therapeutic attributes. Here in, two novel series of benzimidazole-triazole hybrids were designed, synthesised as multi-target EGFR, VEGFR-2 and Topo II inhibitors, and evaluated for anticancer activity. Compounds 5a and 6g wer...

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Detalles Bibliográficos
Autores principales: Othman, Dina I. A., Hamdi, Abdelrahman, Tawfik, Samar S., Elgazar, Abdullah A., Mostafa, Amany S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9858449/
https://www.ncbi.nlm.nih.gov/pubmed/36651111
http://dx.doi.org/10.1080/14756366.2023.2166037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9858449/
https://www.ncbi.nlm.nih.gov/pubmed/36651111
http://dx.doi.org/10.1080/14756366.2023.2166037

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