The molecular mechanism of sialic acid transport mediated by Sialin

Malfunction of the sialic acid transporter caused by various genetic mutations in the SLC17A5 gene encoding Sialin leads to a spectrum of neurodegenerative conditions called free sialic acid storage disorders. Unfortunately, how Sialin transports sialic acid/proton (H(+)) and how pathogenic mutation...

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Detalles Bibliográficos
Autores principales: Hu, Wenxin, Chi, Congwu, Song, Kunhua, Zheng, Hongjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9858498/
https://www.ncbi.nlm.nih.gov/pubmed/36662855
http://dx.doi.org/10.1126/sciadv.ade8346

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9858498/
https://www.ncbi.nlm.nih.gov/pubmed/36662855
http://dx.doi.org/10.1126/sciadv.ade8346

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