Lnc956 regulates mouse embryonic stem cell differentiation in response to DNA damage in a p53-independent pathway

Maintaining genomic stability is crucial for embryonic stem cells (ESCs). ESCs with unrepaired DNA damage are eliminated through differentiation and apoptosis. To date, only tumor suppressor p53 is known to be implicated in this quality control process. Here, we identified a p53-independent quality...

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Detalles Bibliográficos
Autores principales: Ma, Huaixiao, Ning, Yuqi, Wang, Lin, Zhang, Weidao, Zheng, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9858519/
https://www.ncbi.nlm.nih.gov/pubmed/36662856
http://dx.doi.org/10.1126/sciadv.ade9742

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9858519/
https://www.ncbi.nlm.nih.gov/pubmed/36662856
http://dx.doi.org/10.1126/sciadv.ade9742

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