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Locus Coeruleus Dysfunction and Trigeminal Mesencephalic Nucleus Degeneration: A Cue for Periodontal Infection Mediated Damage in Alzheimer’s Disease?

Alzheimer’s disease (AD) is a leading neurodegenerative disease with deteriorating cognition as its main clinical sign. In addition to the clinical history, it is characterized by the presence of two neuropathological hallmark lesions; amyloid-beta (Aβ) and neurofibrillary tangles (NFTs), identified...

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Detalles Bibliográficos
Autores principales: Pisani, Flavio, Pisani, Valerio, Arcangeli, Francesca, Harding, Alice, Singhrao, Sim K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9858796/
https://www.ncbi.nlm.nih.gov/pubmed/36673763
http://dx.doi.org/10.3390/ijerph20021007