Nontraditional Roles of DNA Polymerase Eta Support Genome Duplication and Stability

DNA polymerase eta (Pol η) is a Y-family polymerase and the product of the POLH gene. Autosomal recessive inheritance of POLH mutations is the cause of the xeroderma pigmentosum variant, a cancer predisposition syndrome. This review summarizes mounting evidence for expanded Pol η cellular functions...

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Detalles Bibliográficos
Autor principal: Eckert, Kristin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9858799/
https://www.ncbi.nlm.nih.gov/pubmed/36672916
http://dx.doi.org/10.3390/genes14010175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9858799/
https://www.ncbi.nlm.nih.gov/pubmed/36672916
http://dx.doi.org/10.3390/genes14010175

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