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Epigenetic Repression of RUNX2 and OSX Promoters Controls the Nonmineralized State of the Periodontal Ligament

The nonmineralized state of the mammalian periodontal ligament is one of the hallmarks of vertebrate evolution as it provides resilient and nontraumatic tooth anchorage for effective predation. Here we sought to determine how the chromatin state of key mineralization gene promoters contributes to th...

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Detalles Bibliográficos
Autores principales: Gopinathan, Gokul, Luan, Xianghong, Diekwisch, Thomas G. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9858805/
https://www.ncbi.nlm.nih.gov/pubmed/36672941
http://dx.doi.org/10.3390/genes14010201