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The Role of PARP1 and PAR in ATP-Independent Nucleosome Reorganisation during the DNA Damage Response
The functioning of the eukaryotic cell genome is mediated by sophisticated protein-nucleic-acid complexes, whose minimal structural unit is the nucleosome. After the damage to genomic DNA, repair proteins need to gain access directly to the lesion; therefore, the initiation of the DNA damage respons...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9859207/ https://www.ncbi.nlm.nih.gov/pubmed/36672853 http://dx.doi.org/10.3390/genes14010112 |