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Novel Ground-Up 3D Multicellular Simulators for Synthetic Biology CAD Integrating Stochastic Gillespie Simulations Benchmarked with Topologically Variable SBML Models

The elevation of Synthetic Biology from single cells to multicellular simulations would be a significant scale-up. The spatiotemporal behavior of cellular populations has the potential to be prototyped in silico for computer assisted design through ergonomic interfaces. Such a platform would have gr...

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Detalles Bibliográficos
Autores principales: Matzko, Richard Oliver, Mierla, Laurentiu, Konur, Savas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9859520/
https://www.ncbi.nlm.nih.gov/pubmed/36672895
http://dx.doi.org/10.3390/genes14010154