Fluorescence lifetime-based assay reports structural changes in cardiac muscle mediated by effectors of contractile regulation

Cardiac muscle contraction is regulated by Ca(2+)-induced structural changes of the thin filaments to permit myosin cross-bridge cycling driven by ATP hydrolysis in the sarcomere. In congestive heart failure, contraction is weakened, and thus targeting the contractile proteins of the sarcomere is a...

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Detalles Bibliográficos
Autores principales: Dvornikov, Alexey V., Bunch, Thomas A., Lepak, Victoria C., Colson, Brett A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9859762/
https://www.ncbi.nlm.nih.gov/pubmed/36633587
http://dx.doi.org/10.1085/jgp.202113054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9859762/
https://www.ncbi.nlm.nih.gov/pubmed/36633587
http://dx.doi.org/10.1085/jgp.202113054

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