Pharmacokinetics and bioequivalence evaluation of omeprazole and sodium bicarbonate dry suspensions in healthy Chinese volunteers

Omeprazole and sodium bicarbonate dry suspension are effective treatments for acid-related disorders. This study compared the bioequivalence and safety of the two formulations of omeprazole and sodium bicarbonate powder and assessed how CYP2C19 gene polymorphisms affect pharmacokinetics (PK). A sing...

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Detalles Bibliográficos
Autores principales: Zhang, Rui, Guo, Pengpeng, Zhou, Jinping, Li, Peixia, Wan, Jing, Yang, Chunxiao, Zhou, Jiali, Liu, Yani, Shi, Shaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9859815/
https://www.ncbi.nlm.nih.gov/pubmed/36670124
http://dx.doi.org/10.1038/s41598-022-27286-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9859815/
https://www.ncbi.nlm.nih.gov/pubmed/36670124
http://dx.doi.org/10.1038/s41598-022-27286-5

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