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miR-22 alleviates sepsis-induced acute kidney injury via targeting the HMGB1/TLR4/NF-κB signaling pathway

BACKGROUND: Acute kidney injury (AKI) is a severe complication of sepsis, and is strongly correlated with MicroRNAs (miRNAs). However, the mechanism of miR-22 on sepsis-induced AKI is not clearly understood. The study aimed to explore the role and mechanism of miR-22 on AKI. METHODS: The AKI models...

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Detalles Bibliográficos
Autores principales: Zhang, Jie, Chen, Qi, Dai, Zhuquan, Pan, Huibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9859886/
https://www.ncbi.nlm.nih.gov/pubmed/35960478
http://dx.doi.org/10.1007/s11255-022-03321-2