Long-term in vitro recording of cardiac action potentials on microelectrode arrays for chronic cardiotoxicity assessment

The reliable identification of chronic cardiotoxic effects in in vitro screenings is fundamental for filtering out toxic molecular entities before in vivo animal experimentation and clinical trials. Present techniques such as patch-clamp, voltage indicators, and standard microelectrode arrays do not...

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Detalles Bibliográficos
Autores principales: Iachetta, Giuseppina, Melle, Giovanni, Colistra, Nicolò, Tantussi, Francesco, De Angelis, Francesco, Dipalo, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
in Vitro Systems
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9859891/
https://www.ncbi.nlm.nih.gov/pubmed/36607357
http://dx.doi.org/10.1007/s00204-022-03422-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9859891/
https://www.ncbi.nlm.nih.gov/pubmed/36607357
http://dx.doi.org/10.1007/s00204-022-03422-y

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