Virtual cells in a virtual microenvironment recapitulate early development-like patterns in human pluripotent stem cell colonies

The mechanism by which morphogenetic signals engage the regulatory networks responsible for early embryonic tissue patterning is incompletely understood. Here, we developed a minimal gene regulatory network (GRN) model of human pluripotent stem cell (hPSC) lineage commitment and embedded it into “ce...

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Detalles Bibliográficos
Autores principales: Kaul, Himanshu, Werschler, Nicolas, Jones, Ross D., Siu, M. Mona, Tewary, Mukul, Hagner, Andrew, Ostblom, Joel, Aguilar-Hidalgo, Daniel, Zandstra, Peter W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Resource
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9859929/
https://www.ncbi.nlm.nih.gov/pubmed/36332630
http://dx.doi.org/10.1016/j.stemcr.2022.10.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9859929/
https://www.ncbi.nlm.nih.gov/pubmed/36332630
http://dx.doi.org/10.1016/j.stemcr.2022.10.004

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