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Entropy sorting of single-cell RNA sequencing data reveals the inner cell mass in the human pre-implantation embryo

A major challenge in single-cell gene expression analysis is to discern meaningful cellular heterogeneity from technical or biological noise. To address this challenge, we present entropy sorting (ES), a mathematical framework that distinguishes genes indicative of cell identity. ES achieves this in...

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Detalles Bibliográficos
Autores principales: Radley, Arthur, Corujo-Simon, Elena, Nichols, Jennifer, Smith, Austin, Dunn, Sara-Jane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9859930/
https://www.ncbi.nlm.nih.gov/pubmed/36240776
http://dx.doi.org/10.1016/j.stemcr.2022.09.007