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Entropy sorting of single-cell RNA sequencing data reveals the inner cell mass in the human pre-implantation embryo
A major challenge in single-cell gene expression analysis is to discern meaningful cellular heterogeneity from technical or biological noise. To address this challenge, we present entropy sorting (ES), a mathematical framework that distinguishes genes indicative of cell identity. ES achieves this in...
Autores principales: | Radley, Arthur, Corujo-Simon, Elena, Nichols, Jennifer, Smith, Austin, Dunn, Sara-Jane |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9859930/ https://www.ncbi.nlm.nih.gov/pubmed/36240776 http://dx.doi.org/10.1016/j.stemcr.2022.09.007 |
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