A single cell-based computational platform to identify chemical compounds targeting desired sets of transcription factors for cellular conversion

Cellular conversion can be induced by perturbing a handful of key transcription factors (TFs). Replacement of direct manipulation of key TFs with chemical compounds offers a less laborious and safer strategy to drive cellular conversion for regenerative medicine. Nevertheless, identifying optimal ch...

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Detalles Bibliográficos
Autores principales: Zheng, Menglin, Xie, Bingqing, Okawa, Satoshi, Liew, Soon Yi, Deng, Hongkui, Sol, Antonio del
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9859931/
https://www.ncbi.nlm.nih.gov/pubmed/36400030
http://dx.doi.org/10.1016/j.stemcr.2022.10.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9859931/
https://www.ncbi.nlm.nih.gov/pubmed/36400030
http://dx.doi.org/10.1016/j.stemcr.2022.10.013

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