Aldehyde dehydrogenase 2 alleviates mitochondrial dysfunction by promoting PGC-1α-mediated biogenesis in acute kidney injury

Renal tubular epithelial cells are one of the high energy-consuming cell types, which mainly depend on mitochondrial energy supply. Aldehyde dehydrogenase 2 (ALDH2) is a key enzyme that is involved in alcohol metabolism and mitochondrial oxidative ATP production; however, its function in mitochondri...

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Detalles Bibliográficos
Autores principales: Li, Jiaying, Shi, Xiaoxiao, Chen, Zhixin, Xu, Jiatong, Zhao, Ruohuan, Liu, Yuhao, Wen, Yubing, Chen, Limeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860042/
https://www.ncbi.nlm.nih.gov/pubmed/36670098
http://dx.doi.org/10.1038/s41419-023-05557-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860042/
https://www.ncbi.nlm.nih.gov/pubmed/36670098
http://dx.doi.org/10.1038/s41419-023-05557-x

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