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Single-cell transcriptomics reveals correct developmental dynamics and high-quality midbrain cell types by improved hESC differentiation

Stem cell technologies provide new opportunities for modeling cells in health and disease and for regenerative medicine. In both cases, developmental knowledge and defining the molecular properties and quality of the cell types is essential. In this study, we identify developmental factors important...

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Detalles Bibliográficos
Autores principales: Nishimura, Kaneyasu, Yang, Shanzheng, Lee, Ka Wai, Ásgrímsdóttir, Emilía Sif, Nikouei, Kasra, Paslawski, Wojciech, Gnodde, Sabine, Lyu, Guochang, Hu, Lijuan, Saltó, Carmen, Svenningsson, Per, Hjerling-Leffler, Jens, Linnarsson, Sten, Arenas, Ernest
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860082/
https://www.ncbi.nlm.nih.gov/pubmed/36400027
http://dx.doi.org/10.1016/j.stemcr.2022.10.016