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Single-cell transcriptomics reveals correct developmental dynamics and high-quality midbrain cell types by improved hESC differentiation
Stem cell technologies provide new opportunities for modeling cells in health and disease and for regenerative medicine. In both cases, developmental knowledge and defining the molecular properties and quality of the cell types is essential. In this study, we identify developmental factors important...
Autores principales: | Nishimura, Kaneyasu, Yang, Shanzheng, Lee, Ka Wai, Ásgrímsdóttir, Emilía Sif, Nikouei, Kasra, Paslawski, Wojciech, Gnodde, Sabine, Lyu, Guochang, Hu, Lijuan, Saltó, Carmen, Svenningsson, Per, Hjerling-Leffler, Jens, Linnarsson, Sten, Arenas, Ernest |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860082/ https://www.ncbi.nlm.nih.gov/pubmed/36400027 http://dx.doi.org/10.1016/j.stemcr.2022.10.016 |
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