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The use of chemogenetic actuator ligands in nonhuman primate DREADDs-fMRI

Designer Receptors Exclusively Activated by Designer Drugs (DREADDs) are engineered receptors that allow for genetically targeted, reversible manipulation of cellular activity via systemic drug administration. DREADD induced manipulations are initiated via the binding of an actuator ligand. Therefor...

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Detalles Bibliográficos
Autores principales: Cushnie, Adriana K., Bullock, Daniel N., Manea, Ana M.G., Tang, Wei, Zimmermann, Jan, Heilbronner, Sarah R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860110/
https://www.ncbi.nlm.nih.gov/pubmed/36691404
http://dx.doi.org/10.1016/j.crneur.2022.100072