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The use of chemogenetic actuator ligands in nonhuman primate DREADDs-fMRI
Designer Receptors Exclusively Activated by Designer Drugs (DREADDs) are engineered receptors that allow for genetically targeted, reversible manipulation of cellular activity via systemic drug administration. DREADD induced manipulations are initiated via the binding of an actuator ligand. Therefor...
Autores principales: | Cushnie, Adriana K., Bullock, Daniel N., Manea, Ana M.G., Tang, Wei, Zimmermann, Jan, Heilbronner, Sarah R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860110/ https://www.ncbi.nlm.nih.gov/pubmed/36691404 http://dx.doi.org/10.1016/j.crneur.2022.100072 |
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