Generation of innervated cochlear organoid recapitulates early development of auditory unit

Functional cochlear hair cells (HCs) innervated by spiral ganglion neurons (SGNs) are essential for hearing, whereas robust models that recapitulate the peripheral auditory circuity are still lacking. Here, we developed cochlear organoids with functional peripheral auditory circuity in a staging thr...

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Detalles Bibliográficos
Autores principales: Xia, Mingyu, Ma, Jiaoyao, Wu, Mingxuan, Guo, Luo, Chen, Yan, Li, Geng-lin, Sun, Shan, Chai, Renjie, Li, Huawei, Li, Wenyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860115/
https://www.ncbi.nlm.nih.gov/pubmed/36584686
http://dx.doi.org/10.1016/j.stemcr.2022.11.024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860115/
https://www.ncbi.nlm.nih.gov/pubmed/36584686
http://dx.doi.org/10.1016/j.stemcr.2022.11.024

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